Found 18 matching trials
PolyImmune {Durvalumab (MEDI4736) and Tremelimumab} & Vaccine Orchestrated Treatment for Patients With Advanced/Metastatic Renal Cell Carcinoma PHASE2 Reported in the 2018 NEJM (378; 1277) article, the combination of checkpoin...
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Neoantigen DNA Vaccine in Combination With Nivolumab/Ipilimumab and PROSTVAC in Metastatic Hormone-Sensitive Prostate Cancer PHASE1 This study study aims to elucidate the immune responses to a shared antigen...
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Washington University School of Medicine
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A Screening Study Targeting Tumor-specific Antigens N/A The purpose of this study is to identify patients who may be eligible to pa...
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Miami Cancer Institute
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Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer PHASE2 The investigators hypothesize that a personalized neoantigen vaccine combin...
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Washington University School of Medicine
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GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC PHASE1 This is a single-arm, open-label, multi-site Phase I/IIa study of a persona...
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Johns Hopkins Hospital
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Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Anti-PD-1/PD-L1 Therapy in Patients With Solid Tumors PHASE1 Phase I/II multicenter, open-label, single-arm trial in patients to evaluat...
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Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma PHASE1 This is a single institution, open-label, multi-arm, phase I study assessin...
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Location
Washington University School of Medicine
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Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy PHASE1 This is a phase 1 open-label study to evaluate the safety and immunogenicit...
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Johns Hopkins School of Medicine
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Expanded Access Neoantigen Vaccine in Solid Tumors N/A This is an expanded access use study. Safety data will be collected from pa...
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No Longer Available
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Washington University School of Medicine
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Study Evaluating the Safety Feasibility and Efficacy of ODI-2001 Vaccine, a Personnalized Immunotherapy in Patients With Metastatic or Locally Advanced Colon Cancer or Pancreatic Cancer PHASE1 This is a phase 1, open-label, multicentric study evaluating the safety, fe...
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